Small Extracellular Vesicles/Exosomes Lipidomics

Lipids are important components of cell membranes, various lipid transport and vesicle storage. Due to their diversity of structural and physicochemical properties, lipids can perform a variety of biochemical functions in a variety of cellular processes. As a cellular framework and energy storage substance, lipids account for a large proportion of plants and animals (e.g., about 70% of plasma). In recent years, it has been widely used in the research of plants, animals, microorganisms and other fields. Particularly, studies in related fields have found that lipid metabolism disorders are closely related to a variety of diseases such as cardiovascular diseases, obesity, tumors, diabetes, etc.

 

Exosomal lipidomics refers to the analysis and study of lipid molecules in exosomes to understand the biosynthesis, secretion, transmission, and mechanism of action of exosomes. Exosomal lipid molecules include membrane lipids, triglycerides, cholesterol and other types, and these lipid molecules are involved in many important biological processes, such as cell signaling, cell membrane structure and function maintenance, etc.

 

Services at NextGen Exsome

1.Absolute Quantification of Exosomal Lipidomics

Detection was performed using an absolute lipidome quantification method and standard data analysis was performed, search the Thermo Lipid Search database, which contains 3 million lipid standards, absolute quantification was performed using isotope internal standards.

 

Deliverables:

 

1)A report in PDF format

2)Original machine data in RAW format