TEM Based Small Extracellular Vesicles/Exosome Structural and Morphological Analysis Service

NextGen Exsome provides professional exosome transmission electron microscopy (TEM) testing services to help researchers better understand the morphology and structure of exosomes, and further explore their functions and mechanisms of action. TEM is currently one of the most commonly used methods in exosome morphology research, allowing for the observation of ultra-high-resolution images of exosomes in samples and providing detailed information about exosome morphology and size distribution.

 

At NextGen Exsome, we use the HT7700 TEM from HITACHI in Japan for exosomal observation. As the latest model of the globally best-selling Hitachi TEM H-7000 series, the HT7700 is the most advanced transmission electron microscope developed by Hitachi High-Tech Corporation for the fields of biology, pharmaceuticals, nanotechnology and soft materials.

 

The HT7700 is a revolutionary new TEM with excellent operability and a variety of digital image functions. By unifying the operation of the CCD camera with the microscope unit, it allows for easy operation via the display screen and enables observation in a bright room. Conventional shooting can provide pictures with 4 fields of view: 1um (10000X), 500nm (20000X), 200nm (30000X), and 100nm (60000X), which cater to the publication needs of most researchers.

 

Technical Advantages

1.Resolution:

0.204nm (lattice image @100kV)

 

2.Magnification:

×200~×200,000 high contrast mode

×4,000~×600,000 high magnification mode

×50~×1,000 low magnification mode

 

3.Accelerating Voltage:

40~120 (0.1kV step)

 

4.Maximum Tilt Angle:

+30° (±70° optional)

 

5.Digital Cameras:

1,024×1,024 pixels (2,028×2,048 pixels optional)

 

6.Vacuum System:

TMP×1、RP×1

 

7.Power Supply:

4kVA

 

Services at NextGen Exsome

1.TEM Detection of Small Extracellular Vesicles/Exsome

Observing the morphology of exosomes by TEM.

 

Deliverables:

 

6 pieces of electron microscope raw data in JPG format (1 piece of 1um, 1 piece of 500nm, 1 piece of 200nm, 3 pieces of 100nm field of view).

 

2.TEM Detection of Large Vesicles

Observing the morphology of large vesicles by TEM.

 

Deliverables:

 

6 pieces of electron microscope raw data in JPG format (1 piece of 1um, 3 piece of 500nm, 1 piece of 200nm, 1 pieces of 100nm field of view).

 

3.TEM Detection of Liposomes, Viruses, etc

Observing the morphology of liposomes and other samples by TEM.

 

Deliverables:

 

6 pieces of electron microscope raw data in JPG format (1 piece of 1um, 1 piece of 500nm, 1 piece of 200nm, 3 pieces of 100nm field of view).